XV International Symposium on Atherosclerosis 2009
Satellite Symposia
Pre-Satellite Symposia
June 11-13, 2009
The Biology of Atherosclerosis – June 12-13, 2009
Nutrition, Lifestyle and Atherosclerosis – June 11-13, 2009
Genetics and Atherosclerosis – June 11-13, 2009
CHANGE IN VENUE NOTICE
The Vascular Biology Satellite Symposium scheduled at Chatham Bars Inn on Cape Cod, June 12 – 13, 2009 has been moved to the Boston Copley Marriott. The original program schedule of the meeting remains the same.
We hope that this move will allow more scientists to participate at a lower cost for both housing and travel. We feel this will particularly benefit the many physicians and researchers located in the Boston area, especially those in the early stages of their careers.
We appreciate your understanding.
Respectfully,
ISA Satellite Organizers
The Biology of Atherosclerosis - June 12-13, 2009
Chatham Bars Inn and Conference Center
297 Shore Road
Chatham, MA 02633 USA
(+1) 800-527-4884
www.chathambarsinn.com
Getting to the Chatham Bars Inn and Conference Center
Hotel Accommodations: A limited number of rooms have been reserved at the Chatham Bars Inn and Conference Center for symposium participants at a discounted rate of $379 USD per night plus applicable taxes. A resort fee of $14 USD per night also applies. Please call the hotel directly to make your reservations at (+1) 800-527-4884 or (+1) 508-945-0096. The deadline for the discounted rate is May 11, 2009. Please mention the International Symposium on Atherosclerosis when booking your reservation.
Chairpersons: M Gimbrone, Jr. (USA), P Libby (USA)
Scope of the Program
While much progress has been made in our understanding of the process known as atherosclerosis which clogs coronary arteries, much remains to be learned about the development of such lesions and what causes them to rupture and occlude the artery causing a heart. Statins, drugs which reduce the levels of low density lipoproteins in the blood stream and limit inflammation can significantly reduce the risk of heart disease. We are beginning to understand some of the mechanisms whereby these agents have their beneficial effects directly in the artery wall. This satellite symposium will address the need to understand how to stabilize existing plaque in the artery wall to prevent further disease in subjects who already have coronary artery disease; the need to know how to protect the artery wall from build up of atherosclerosis, as well as to understand the interactions of plasma lipoproteins with the artery wall; the need to elucidate the role of oxidative stress and inflammation in the development of atherosclerosis, as well as the mechanisms for clot formation in arteries already affected by fatty plaque, and the need for better ways to image disease within the artery and ways to determine which plaques are vulnerable to rupture and clot formation.
Goals and Objectives
At the conclusion of this activity, participants should be able to:
- Understand how atherosclerosis develops in the artery, and how one can protect individuals from this process;
- Demonstrate increased knowledge with regard to how plasma lipoproteins, specifically triglyceride-rich lipoproteins, low density lipoproteins, and high density lipoproteins, underact with the artery wall;
- Be able to assess the role of oxidation in the development of atherosclerosis; and
- Understand the mechanisms of clot formation in atherosclerotic plaques, as well as the methods for imaging atherosclerosis and vulnerable plaques in the artery.
Friday, June 12, 2009
- Session 1:
- Atheroprotection
Chairs: MA Gimbrone (USA), GK Hansson (Sweden) - 9:00 - 9:30 AM
- Immune Mechanisms in Atheroprotection
GK Hansson (Sweden) - 9:30 - 10:00 AM
- Role of Cytokines in Atheroprotection
Z Mallat (France) - 10:00 - 10:30 AM
- Endothelial Atheroprotective Genes
G Garcia-Cardena (USA) - 10:30 - 11:00 AM
- Discussion
MA Gimbrone (USA) - 11:00 AM - 1:00 PM
- Poster Session and Lunch
- Session 2:
- Lipid Interactions with Cells Involved in Atherosclerosis
Chairs: T van Berkel (The Netherlands), CA Reardon (USA) - 1:00 - 1:30 PM
- Macrophage Cholesterol Homeostasis and Atherogenesis
T van Berkel (The Netherlands) - 1:30 - 2:00 PM
- Adaptive Immunity, Lipids, and Atherogenesis
CA Reardon (USA) - 2:00 - 2:30 PM
- Regulation of Macrophage Cholesterol Transport by Nuclear Receptors
B Staels (France) - 2:30 - 3:00 PM
- Discussion
T van Berkel (The Netherlands) - 3:00 - 3:30 PM
- Coffee Break
- Session 3:
- Arterial Oxidative Stress
Chair: J Witztum (USA) - 3:30 - 4:00 PM
- Roles Of Inflammation And Endoplasmic Reticulum Stress In The Progression And Rapture Of Atherosclerotic Plaques
M Kitakaze (Japan) - 4:00 - 4:30 PM
- Oxidation - Specific Epitopes Are A Target Of Innate Immunity
J Witztum (USA) - 4:30 - 5:00 PM
- Oxidized And HDL Function
SJ Hazen (USA) - 5:00 - 5:30 PM
- Discussion
J Witztum (USA)
Saturday, June 13, 2009
- Session 4:
- Mechanisms of Atherothrombosis
Chair: R Nagai (Japan) - 9:00 - 9:30 AM
- The Inflammation/Thrombosis Nexus
C Weber (Germany) - 9:30 - 10:00 AM
- Obesity/Dysmetabolism and Atherothrombosis
R Nagai (Japan) - 10:00 - 10:30 AM
- Mast Cells In Atherosclerosis, Aneurysm, And Obesity
GP Shi (USA) - 10:30 - 11:00 AM
- Discussion
R Nagai (Japan) - 11:00 AM - 1:00 PM
- Poster Session and Lunch
- Session 5:
- Imaging Arterial Pathobiology
Chair: P Libby (USA) - 1:00 - 1:30 PM
- Optical Analysis of TLR Function in Atheroma
L Curtiss (USA) - 1:30 - 2:00 PM
- Molecular Imaging of Cardiovascular Calcification
E Aikawa (USA) - 2:00 - 2:30 PM
- FDG Imaging of Atheroma
J Rudd (UK) - 2:30 - 3:00 PM
- Discussion and Concluding Remarks
P Libby (USA)
Nutrition, Lifestyle and Atherosclerosis – June 11-13, 2009
Mount Washington Resort at Bretton Woods
Route 302
Bretton Woods, NH 03575
(+1) 800-314-1752
www.mountwashingtonresort.com
Getting to the Mount Washington Resort at Bretton Woods
Hotel Accommodations: A limited number of rooms have been reserved at the Mount Washington Resort at Bretton Woods for symposium participants at a discounted rate of $250 USD per night plus applicable taxes. Please call the hotel directly to make your reservations at (+1) 800-314-1752 or (+1) 603-278-1000. The deadline for the discounted rate is May 28, 2009. Please mention the International Symposium on Atherosclerosis when booking your reservation.
Chairpersons: A Lichtenstein (USA), MB Katan (Netherlands)
Scope of the Program
Dietary and lifestyle changes are the primary treatment modality for cardiovascular risk reduction, through both LDL-C lowering and management of the metabolic syndrome. The recent EUROACTION program, developed by the European Society of Cardiology, demonstrates that a multidisciplinary, family-based preventive cardiology approach can significantly improve lifestyle and metabolic risk factors for cardiovascular disease in both a hospital and general practice setting. There is a need for similar programs and strategies around the world that can increase patient awareness and promote lasting dietary and lifestyle changes. Physician surveys confirm this need for more consistent and effective counseling of patients about diet, exercise, and smoking cessation, particularly in routine. This satellite symposium will contribute to the ongoing discussion on this topic by providing physicians, other health care providers, and scientists with an update on cutting-edge issues in nutrition and lifestyle research, with the goal of improving patient care and clinical outcomes. This satellite symposium will also address the effect of dietary composition and of specific nutrients/supplements on cardiovascular risk, in order to aid physicians in making informed decisions regarding counseling, prevention, and treatment.
Goals and Objectives
At the conclusion of this activity, participants should be able to:
- Demonstrate increased knowledge of various strategies for dietary modification in the reduction of cardiovascular risk;
- Appraise the safety and efficacy of various dietary plans, nutrients, and supplements in terms of cardiovascular risk reduction, in order to guide patients to make appropriate dietary choices; and
- Discuss current cutting-edge issues in the field of nutrition and lifestyle research with colleagues.
Thursday, June 11, 2009
- 8:00 - 8:30 PM
- Introductory Lecture
Diet and Cardiovascular Disease: The Way Ahead
MB Katan (The Netherlands) - 8:30 - 8:45 PM
- Discussion
MB Katan (The Netherlands), A Lichtenstein (USA)
Friday, June 12, 2009
- Session 1:
- Fatty Acids and CVD Risk
Chair: A Lichtenstein (USA) - 9:00 - 9:30 AM
- Effect Of Animal and Industrial Trans Fatty Acids On Blood Lipoproteins In Humans
B Lamarche (Canada) - 9:30 - 10:00 AM
- Effect Of Conjugated Linoleic Acid, An Animal Trans Fatty Acid, On Blood Lipoproteins In Humans
B Lamarche (Canada) - 10:00 - 10:30 AM
- Changing The Food Environment - A Case Study; Partially Hydrogenated Fat And New York City
A Lichtenstein (USA) - 10:30 - 11:00 AM
- Dietary Fatty Acids and Heart Disease
P Nestel (Australia) - 11:00 AM - 1:00 PM
- Poster Session and Lunch
- Session 2:
- Macronutrient and Energy balance
Chair: F Sacks (USA) - 1:00 - 1:30 PM
- Weight Loss: Nutritional and Behavioural Determinants
F Sacks (USA) - 1:30 - 2:00 PM
- Fructose Consumption: Recent Results and their Implications
K Stanhope (USA) - 2:00 - 2:30 PM
- Dietary Carbohydrate (Glycemic Index)
T Wolever (Canada) - 2:30 - 3:00 PM
- Panel/Audience Discussion: Does Macronutrient Composition Matter?
F Sacks (USA) - 3:00 - 3:30 PM
- Break and Poster Viewing
- Session 3:
- Plant sterols
Chair: H Gylling (Finland) - 3:30 - 4:00 PM
- Plant Stanols - Efficacy and Safety
H Gylling (Finland) - 4:30 - 5:00 PM
- Plant Sterols - Efficacy and Safety
PJH Jones (Canada) - 4:30 - 5:00 PM
- Cholesterol Absorption/Synthesis Markers for Cardiovascular Disease Risk
NR Matthan (USA) - 5:00 - 5:30 PM
- Panel/Audience Discussion: Are Plant Sterols Safe and Effective In Lowering Coronary Heart Disease Risk?
H Gylling (Finland) - Session 4:
- Where Are With Omega 3 Fatty Acids?
Chair: EJ Schaefer (USA) - 8:00 - 9:10 PM
IA Brouwer (The Netherlands)
R Marchioli (Italy)
EJ Schaefer (USA)
Saturday, June 13, 2009
- Session 5:
- Nutrient Supplements
Chair: A Olsson (Sweden) - 9:00 - 9:30 AM
- B-Vitamins and Cardiovascular Disease
R Clarke (UK) - 9:30 - 10:00 AM
- Anti-Oxidants - Post Mortem
A Olsson (Sweden) - 10:00 - 10:30 AM
- Alcohol, Wine Polyphenols, and CVD Risk
E Rimm (USA) - 10:30 - 11:00 AM
- Panel/Audience Discussion: Do Supplements Have a Role in the Prevention of Coronary Heart Disease - Lessons Learned?
A Olsson (Sweden) - 11:00 AM - 1:00 PM
- Posters and Lunch
- Session 6:
- Bioactive Substances in Food and Beverages
Chair: D Grassi (Italy) - 1:00 -1:30 PM
- Cocoa, Blood Pressure, and Cardiovascular Disease
D Grassi (Italy) - 1:30 - 2:00 PM
- Tea And Flavonoids
P Hollman (The Netherlands) - 2:00 - 2:30 PM
- Coffee and Cafestol
ML Ricketts (USA) - 2:30 - 3:00 PM
- Panel/Audience Discussion: Flavonoids And Cardiovascular Risk Factors: Focusing On Possible Pathophysiological Mechanisms Of Action
Chair: D Grassi (Italy) - 3:00 - 3:30 PM
- Coffee Break
- Session 7:
- Components of Unified Dietary Guidance
- 3:30 - 4:00 PM
- Dietary Guidance - Where Are We Headed?
A Lichtenstein (USA) - 4:00 - 4:30
- Closing Discussion
A Lichtenstein (USA), MB Katan (The Netherlands)
Genetics and Atherosclerosis – June 11-13, 2009
Bar Harbor, ME
This symposium has been cancelled.